Pre-seed Biotech Investors in the US
We've mapped 17 of the most active pre-seed Biotech investors funding founders in the US, with cheques $25K–$100M.
- Pre-seed17
- Seed17
- Series A14
- Series B10
- Series C+10
We've mapped 17 of the most active pre-seed Biotech investors funding founders in the US — 17 VCs. Cheque sizes across this segment run $25K–$100M.
When raising pre-seed for a Biotech company in the US, founders should lead with the investors whose stage and cheque size actually match the round — not just the best-known names. 17 of these profiles have been verified in the last review pass. Sign in to see each investor's full thesis, cheque range, and how closely they fit your specific company.
Red Cedar Ventures
Venture subsidiary of the MSU Research Foundation supporting early-stage high-tech startups emerging from Michigan State University. Sign in to see full profile →
Hearst Ventures
Corporate VC arm of Hearst Communications (since 1995) investing in media, information, and technology. Sign in to see full profile →
Khosla Ventures
Khosla Ventures is a Menlo Park, California venture capital firm founded in 2004 by Vinod Khosla. Sign in to see full profile →
First Round Capital
First Round Capital is a US seed-stage venture firm founded in 2004 by Josh Kopelman and Howard Morgan, with offices in San Francisco (HQ), New York and Phil… Sign in to see full profile →
8VC
8VC is an Austin, Texas technology investment firm founded in 2015 by Joe Lonsdale after the wind-down of Formation 8. Sign in to see full profile →
Alumni Ventures
Alumni Ventures is a Manchester, New Hampshire venture capital firm that gives individual accredited investors access to venture and late-stage private inves… Sign in to see full profile →
Lux Capital
Lux Capital is a New York-based science and tech VC (founded 2000 by Peter Hebert, Robert Paull, and Josh Wolfe) with $7B+ AUM. Sign in to see full profile →
SOSV
SOSV is a multi-stage venture capital firm investing in deep tech for human and planetary health, from physical AI and hard tech to therapeutics, energy and … Sign in to see full profile →
BoxGroup
Investor built in NYC and SF backing founders at the earliest stage, from pre-seed to as late as Series A, with cheques of up to $1M and companies funded any… Sign in to see full profile →
DCVC
DCVC (Data Collective) is a deep-tech venture capital firm founded in 2010 by Matt Ocko and Zachary Bogue, with offices in Palo Alto and San Francisco. Sign in to see full profile →
Norwest Venture Partners
Lead, Co-Invest One of the most seasoned venture capital and PE investor active for over the last 60 years and having invested in more than 700 companies spa… Sign in to see full profile →
South Park Commons
San Francisco-based community for founders and technologists exploring what to build, with spaces in San Francisco, New York and Bengaluru. Sign in to see full profile →
OrbiMed
Global healthcare investment firm managing ~$20bn across public and private funds, with 150+ professionals in NYC, SF, Shanghai, Mumbai, Herzliya, and beyond. Sign in to see full profile →
AlleyCorp
Looking at companies from the idea stage to 50K+ in MRR We are tech pioneers, investors, and entrepreneurs. We build and invest in transformative companies Sign in to see full profile →
Madrona Venture Group
Seattle-based VC backing founding teams at seed, early and acceleration stages in Seattle, the Bay Area and beyond, across AI and intelligent apps, enterpris… Sign in to see full profile →
Pear VC
Pre-seed and seed VC in Palo Alto backing founders from idea to early traction across consumer, SaaS, enterprise, healthcare, fintech, AI and deep tech. Sign in to see full profile →
CRV
CRV (formerly Charles River Ventures) - top-tier early-stage VC since 1970, ~$1.5B AUM, 600+ investments including DoorDash, Airtable, Patreon, Drift. Sign in to see full profile →
Directory last updated: November 2026.
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