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Pre-seed Healthtech Investors in the US

We've mapped 20 of the most active pre-seed Healthtech investors funding founders in the US, with cheques $25Kโ€“$100M.

Stages they backof 20 firms
  • Pre-seed20
  • Seed20
  • Series A20
  • Series B16
  • Series C+13
A firm counts at every stage it invests in.

We've mapped 20 of the most active pre-seed Healthtech investors funding founders in the US โ€” 20 VCs. Cheque sizes across this segment run $25Kโ€“$100M.

When raising pre-seed for a Healthtech company in the US, founders should lead with the investors whose stage and cheque size actually match the round โ€” not just the best-known names. 20 of these profiles have been verified in the last review pass. Sign in to see each investor's full thesis, cheque range, and how closely they fit your specific company.

VC
Verified Nov 2026
Red Cedar Ventures logo

Red Cedar Ventures

Pre-seed to Series B
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLBiotechClimate+3 more

Venture subsidiary of the MSU Research Foundation supporting early-stage high-tech startups emerging from Michigan State University. Sign in to see full profile โ†’

VC
Verified May 2026
Applied Ventures logo

Applied Ventures

Pre-seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLClimateDeeptech+5 more

Applied Ventures is the corporate venture capital arm of Applied Materials (NASDAQ: AMAT), founded 2006 and based in Santa Clara, CA. Sign in to see full profile โ†’

VC
Verified May 2026
Hearst Ventures logo

Hearst Ventures

Pre-seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
SaaSMarketplacesMedia+10 more

Corporate VC arm of Hearst Communications (since 1995) investing in media, information, and technology. Sign in to see full profile โ†’

VC
Verified Nov 2026
Khosla Ventures logo

Khosla Ventures

Pre-seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLBiotechClimate+9 moreGeneralist

Khosla Ventures is a Menlo Park, California venture capital firm founded in 2004 by Vinod Khosla. Sign in to see full profile โ†’

VC
Verified Nov 2026
First Round Capital logo

First Round Capital

Pre-seed to Series A
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLClimateConsumer+7 moreGeneralist

First Round Capital is a US seed-stage venture firm founded in 2004 by Josh Kopelman and Howard Morgan, with offices in San Francisco (HQ), New York and Philโ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
Eclipse logo

Eclipse

Pre-seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
HealthtechMobilityRobotics+5 more

Palo Alto VC with $2B+ AUM investing in physical-economy startups: manufacturing, logistics, supply chain, energy, defense, robotics. Sign in to see full profile โ†’

VC
Verified Nov 2026
8VC logo

8VC

Pre-seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLBiotechClimate+7 more

8VC is an Austin, Texas technology investment firm founded in 2015 by Joe Lonsdale after the wind-down of Formation 8. Sign in to see full profile โ†’

VC
Verified Nov 2026
Alumni Ventures logo

Alumni Ventures

Pre-seed ยท Seed ยท Series A, C+
๐Ÿ‡บ๐Ÿ‡ธUS
BiotechAI/MLHealthtech+6 more

Alumni Ventures is a Manchester, New Hampshire venture capital firm that gives individual accredited investors access to venture and late-stage private invesโ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
Lux Capital logo

Lux Capital

Pre-seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLBiotechClimate+7 more

Lux Capital is a New York-based science and tech VC (founded 2000 by Peter Hebert, Robert Paull, and Josh Wolfe) with $7B+ AUM. Sign in to see full profile โ†’

VC
Verified Nov 2026
SV Angel logo

SV Angel

Pre-seed to Series B
๐Ÿ‡บ๐Ÿ‡ธUS
EdTechSaaSFintech+4 more

San Francisco angel firm founded by Ron Conway investing in 100+ early-stage AI/software/IT startups per year; portfolio includes Facebook, Twitter, Airbnb, โ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
SOSV logo

SOSV

Pre-seed to Series A
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLBiotechClimate+5 more

SOSV is a multi-stage venture capital firm investing in deep tech for human and planetary health, from physical AI and hard tech to therapeutics, energy and โ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
Spark Capital logo

Spark Capital

Pre-seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLClimateConsumer+7 more

Invests in: Europe, Israel, USA, Canada, Asia, Worldwide VC firm investing and partnering with world-changing in companies. Sign in to see full profile โ†’

VC
Verified Nov 2026
Kindred Ventures logo

Kindred Ventures

Pre-seed to Series B
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLHealthtechRobotics+4 more

Kindred Ventures is a San Francisco venture capital firm that invests at the earliest stages in founders building with technology and science, across AI, cryโ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
Greylock logo

Greylock

Pre-seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
HealthtechSaaSAI/ML+8 more

Greylock is a venture capital firm founded in 1965 and headquartered in Menlo Park, California, that focuses on early-stage companies; most of its investmentโ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
BoxGroup logo

BoxGroup

Pre-seed to Series A
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLBiotechClimate+6 more

Investor built in NYC and SF backing founders at the earliest stage, from pre-seed to as late as Series A, with cheques of up to $1M and companies funded anyโ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
DCVC logo

DCVC

Pre-seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
CyberSaaSFood & Ag+8 more

DCVC (Data Collective) is a deep-tech venture capital firm founded in 2010 by Matt Ocko and Zachary Bogue, with offices in Palo Alto and San Francisco. Sign in to see full profile โ†’

VC
Verified Nov 2026
Gaingels logo

Gaingels

Pre-seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLHealthtechFintech+4 more

Investor community of LGBTQ+ people and allies that co-invests with select venture capital leads in companies building diverse and inclusive teams, from seedโ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
AVP logo

AVP

Pre-seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLCyberSaaS+7 more

Global VC (AVP) with $1.2bn AUM across early, growth and fund-of-funds; offices in NY, London and Paris. Sign in to see full profile โ†’

VC
Verified Nov 2026
Norwest Venture Partners logo

Norwest Venture Partners

Pre-seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
BiotechConsumerSaaS+3 more

Lead, Co-Invest One of the most seasoned venture capital and PE investor active for over the last 60 years and having invested in more than 700 companies spaโ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
SignalFire logo

SignalFire

Pre-seed to Series B
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLHealthtechRobotics+4 more

San Francisco-based AI-native VC with ~$3bn AUM, investing pre-seed to Series B in applied AI across healthcare, cybersecurity, infra, consumer and enterprise. Sign in to see full profile โ†’

Directory last updated: November 2026.

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