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Seed B2B SaaS Investors in the US

We've mapped 10 of the most active seed B2B SaaS investors funding founders in the US, with cheques $100K–$15M.

We've mapped 10 of the most active seed B2B SaaS investors funding founders in the US — 10 VCs. Cheque sizes across this segment run $100K–$15M.

When raising seed for a B2B SaaS company in the US, founders should lead with the investors whose stage and cheque size actually match the round — not just the best-known names. 10 of these profiles have been verified in the last review pass. Sign in to see each investor's full thesis, cheque range, and how closely they fit your specific company.

VCVerified May 2026

Ripple VC

Pre-seed · Seed
🇺🇸US
AI/MLBiotechSaaS+3 more

San Francisco-based seed-stage VC backing disruptive technology founders building for emerging markets, with a focus on African technology companies; led by … Sign in to see full profile →

VCVerified May 2026

Redwood Partners

Seed · Series A
🇺🇸US
ConsumerSaaSMedia

Early-stage VC investment firm founded in 1994 supporting the talent needs and growth of technology-enabled companies. Sign in to see full profile →

VCVerified May 2026

Oriza Ventures

Seed · Series A · Series B
🇺🇸US
AI/MLBiotechSaaS+3 more

Early-stage VC headquartered in Santa Clara investing in US tech startups with cross-border China expansion expertise. Sign in to see full profile →

VCVerified May 2026

Leawood Venture Capital

Pre-seed · Seed · Series A · Series B
🇺🇸US
AI/MLCyberSaaS+3 more

Leawood Kansas-based early-stage VC investing in technology companies across the US since 2017. Sign in to see full profile →

VCVerified May 2026

IBM Ventures

Seed · Series A · Series B · Later
🇺🇸US
AI/MLClimateCyber+2 more

IBM's $500M+ corporate venture arm backing early-stage AI, quantum, security, data, sustainability startups. Sign in to see full profile →

VCVerified May 2026

Emerald Development Manager

Seed · Series A · Series B
🇺🇸US
AI/MLBiotechClimate+4 more

New York-based early-stage VC backing elite scientific/engineering teams in cybersecurity/SaaS, biotech/healthcare IT, and clean tech/industrial tech. Sign in to see full profile →

VCVerified May 2026

DHVC

Pre-seed · Seed · Series A · Series B
🇺🇸US
AI/MLBiotechConsumer+6 more

Palo Alto VC (formerly Danhua Capital) investing in AI, AR/VR, robotics, fintech, healthcare, and enterprise tech. Sign in to see full profile →

VCVerified May 2026

Bertelsmann Digital

Seed · Series A · Series B
🇺🇸US
Web3SaaSFintech+2 more

Bertelsmann's NYC-based corporate VC investing in seed/early-stage SaaS, fintech, web3, and next-gen media. Sign in to see full profile →

VCVerified May 2026

Applied Ventures

Pre-seed · Seed · Series A · Series B · Later
🇺🇸US
AI/MLClimateDeeptech+5 more

Applied Ventures is the corporate venture capital arm of Applied Materials (NASDAQ: AMAT), founded 2006 and based in Santa Clara, CA. Sign in to see full profile →

VCVerified May 2026

Valar Ventures

Pre-seed · Seed · Series A · Series B
🇺🇸US
SaaSFintech

Manhattan-based VC co-founded by Peter Thiel, Andrew McCormack and James Fitzgerald in 2010; focuses on international fintech outside Silicon Valley (Wise, N… Sign in to see full profile →

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Directory last updated: May 2026