VC Firms in San Francisco
We've mapped 20 of the most active VC firms in San Francisco, with cheques $50K–$300M.
- Pre-seed8
- Seed18
- Series A17
- Series B13
- Series C+7
We've mapped 20 of the most active VC firms investing in San Francisco — ranked by how recently and how thoroughly each profile has been verified. Cheque sizes across this segment run $50K–$300M.
Not every one of these VC firms is a fit for every round — they differ on stage, cheque size, and sector focus, and the best-known name is rarely the best match. 20 of these profiles have been verified in the last review pass. Sign in to see each investor's full thesis, cheque range, and how closely they fit your specific company.
M12
Microsoft's venture capital fund, investing in seed through Series B companies in AI apps, security for AI, AI cloud infrastructure, AI data ops and models, … Sign in to see full profile →
S.R. One
Trans-Atlantic biotech venture capital firm (former GSK venture arm); offices in San Francisco and London; $600M Fund II. Sign in to see full profile →
Greenoaks
Greenoaks is a San Francisco investment firm, founded in 2012 by Neil Mehta and Benny Peretz, that makes concentrated, long-term investments in technology-en… Sign in to see full profile →
Citi Ventures
Citi's venture arm, investing in and partnering with startups transforming financial services, from seed to Series F and beyond, across fintech, AI and data,… Sign in to see full profile →
Creative Ventures
Looking at companies from pre-product to those that have shown product-market fit Sign in to see full profile →
11.2 Capital
Early-stage VC investing in breakthrough deep tech: AI, cybersecurity, quantum, robotics, new space, bioengineering, climate. Sign in to see full profile →
First Round Capital
First Round Capital is a US seed-stage venture firm founded in 2004 by Josh Kopelman and Howard Morgan, with offices in San Francisco (HQ), New York and Phil… Sign in to see full profile →
Salesforce Ventures
Salesforce Ventures is the venture arm of Salesforce, based in San Francisco, investing in enterprise technology companies from seed through growth since 2009. Sign in to see full profile →
SV Angel
San Francisco angel firm founded by Ron Conway investing in 100+ early-stage AI/software/IT startups per year; portfolio includes Facebook, Twitter, Airbnb, … Sign in to see full profile →
SOSV
SOSV is a multi-stage venture capital firm investing in deep tech for human and planetary health, from physical AI and hard tech to therapeutics, energy and … Sign in to see full profile →
Kindred Ventures
Kindred Ventures is a San Francisco venture capital firm that invests at the earliest stages in founders building with technology and science, across AI, cry… Sign in to see full profile →
Iconiq Capital
San Francisco-based hybrid family office and growth-stage VC (ICONIQ Growth) backing category-defining technology companies in enterprise software, infrastru… Sign in to see full profile →
Coinbase Ventures
Coinbase Ventures invests in exceptional founders who share Coinbase’s mission of creating more economic freedom for the world. Sign in to see full profile →
DCVC
DCVC (Data Collective) is a deep-tech venture capital firm founded in 2010 by Matt Ocko and Zachary Bogue, with offices in Palo Alto and San Francisco. Sign in to see full profile →
Forerunner Ventures
Forerunner Ventures is a San Francisco-based venture capital firm founded in 2010 by Kirsten Green, dedicated to the modern consumer. Sign in to see full profile →
SignalFire
San Francisco-based AI-native VC with ~$3bn AUM, investing pre-seed to Series B in applied AI across healthcare, cybersecurity, infra, consumer and enterprise. Sign in to see full profile →
South Park Commons
San Francisco-based community for founders and technologists exploring what to build, with spaces in San Francisco, New York and Bengaluru. Sign in to see full profile →
CapitalG
Alphabet's independent growth-stage equity fund (formerly Google Capital, rebranded CapitalG in 2016); $50-200M cheques into tech companies at Series B and l… Sign in to see full profile →
Founders Fund
Founders Fund is a San Francisco venture capital firm founded in 2005 by Peter Thiel, Ken Howery and Luke Nosek. Sign in to see full profile →
Headline
Global VC (formerly e.ventures) with teams in the US, Europe, Asia, and Brazil; invests across fintech, e-commerce, software, digital health, and consumer. Sign in to see full profile →
Directory last updated: November 2026.
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